Rare Disease · Prior Authorization Intelligence

Stop guessing.
Get approved.

Select your drug, payer, and state. PathToApproval walks your office through every step — from benefits investigation through post-approval monitoring.

Request Access → See how it works
Currently Available Drugs
ATTR Amyloidosis
eplontersen (Wainua)
AstraZeneca · hATTR-PN
vutrisiran (Amvuttra)
Alnylam · hATTR-PN + ATTR-CM
acoramidis (Attruby)
BridgeBio Pharma · ATTR-CM
Hereditary Angioedema (HAE)
lanadelumab (Takhzyro)
Takeda · Prophylaxis
berotralstat (Orladeyo)
BioCryst · Prophylaxis
garadacimab (Andembry)
CSL Behring · Prophylaxis
donidalorsen (Dawnzera)
Ionis · Prophylaxis
sebetralstat (Ekterly)
KalVista · Acute Treatment
C1-INH SC (Haegarda)
CSL Behring · Prophylaxis
14
Workflow Modules
9
Live Drug Modules
7
States Live
2
Disease States
Platform Features
Everything your office needs before a PA is submitted.
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Patient Intake & Readiness Score
Enter clinical data only — no patient identifiers. PathToApproval scores readiness, identifies blockers, and generates a personalized action plan before you submit a single form.
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Benefits Investigation Playbook
Select the patient's plan and get the exact call script, submission route, and red flags for that specific payer. No guessing which number to call or what to ask.
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Denial Pathway Intelligence
A complete five-step escalation ladder from step therapy override through external independent review — including the state law protections most offices never know exist.
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AI-Personalized Appeal Letters
Seven document types drafted by AI based on the patient's specific profile — medical necessity, peer-to-peer prep memos, step therapy override letters, and more.
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Reauthorization Workflow
Month-by-month timeline, required documentation checklist, and baseline tracking guide to protect against therapy gaps at the 12-month renewal.
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Affordability & Patient Support
Every savings program, independent foundation, and patient support resource — with eligibility criteria and enrollment contacts in one place.
Who It's For
Built for rare disease office staff.

Prior authorization for rare disease therapeutics is uniquely complex — multiple payer types, evolving criteria, high denial rates. PathToApproval was built by someone who works in this space every day.

Neurology and cardiology rare disease physician offices
Prior authorization coordinators and office managers
Practices managing hATTR-PN, ATTR-CM, Hereditary Angioedema (HAE), and expanding rare disease portfolios
Offices working across multiple payer types and states simultaneously
Payer Coverage
Live payers. More coming.
CT · NY · MA · ME · VT · NH · RI
Aetna Commercial
UnitedHealthcare
Cigna Commercial
Medicare Part B
BCBS Massachusetts
Tufts Health Plan
Harvard Pilgrim
CDPHP (NY)
Healthfirst (NY)
EmblemHealth (NY)
MVP Health Care
Anthem (ME/NH)
BCBS Vermont
Martin's Point (ME)
Neighborhood Health (RI)
CT Medicaid (HUSKY)
NY Medicaid
NH Medicaid
RI Medicaid
More payers — expanding